Three-in-One Aptamer-siRNA Chimera Used to Target Breast Cancer in Mice

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Three-in-One Aptamer-siRNA Chimera Used to Target Breast Cancer in Mice 20%–30% of breast cancer is characterized by HER2 overexpression that correlates with poor prognosis, high aggressiveness, and extensive drug resistance. Resistance to HER2-targeted therapies is associated with increased levels of other HER family receptors; also, antibody combinations have their limitations, with high immunogenicity and high […]

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