Study Finds T-Cell Receptors Operate Solo, Discovery Could Change Course of Immunology Research

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Study Finds T-Cell Receptors Operate Solo, Alters Immunology Research T cell antigen recognition requires T cell antigen receptors (TCRs) engaging MHC-embedded antigenic peptides (pMHCs) within the contact region of a T cell with its conjugated antigen-presenting cell. Despite micromolar affinities, T cells respond to even a single antigenic pMHC, and higher-order TCRs have been postulated […]

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