First CRISPR-Cas9 Blocking Small Molecule Identified

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First CRISPR-Cas9 Blocking Small Molecule Identified In a recent discovery, the first small-molecule inhibitor of the Streptococcus pyogenes Cas9 (SpCas9) protein has been identified by scientists that can enable more precise control over CRISPR-Cas9-based genome editing. The investigators screened a selection of small molecules to identify substances which disrupt the binding of SpCas9 to DNA […]

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